N-Ethylbenzylamine → HCID 22504801, compound

HRID 1814172Notes

Reaction equation

HRID 1814172 reaction equation
COC(=O)COC1C=C(OC)C(SCCC=O)=CC=1C.C(NCC)C1C=CC=CC=1.C[O:32][C:33](=[O:64])[CH2:34][O:35][C:36]1[CH:41]=[C:40]([O:42][CH3:43])[C:39]([S:44][CH2:45][CH2:46][CH2:47][N:48]([CH2:61][CH3:62])[C:49]2[CH:54]=[CH:53][C:52]([C:55]3[CH:60]=[CH:59]C=CC=3)=CN=2)=[CH:38][C:37]=1[CH3:63]>>[CH2:49]([N:48]([CH2:61][CH3:62])[CH2:47][CH2:46][CH2:45][S:44][C:39]1[C:40]([O:42][CH3:43])=[CH:41][C:36]([O:35][CH2:34][C:33]([OH:32])=[O:64])=[C:37]([CH3:63])[CH:38]=1)[C:54]1[CH:53]=[CH:52][CH:55]=[CH:60][CH:59]=1

Participants

4

Reactant 3

HCID 84352N-EthylbenzylamineHCID 20770817(4-{3-[Ethyl-(5-phenyl-pyridin-2-yl)-amino]-propylsulfanyl}-5-methoxy-2-methyl-phenoxy)-acetic acid methyl esterHCID 20770844HCID 20770844, compound

Product 1

HCID 22504801HCID 22504801, compound

Procedure

Compound 64A and benzyl-ethyl-amine were reacted in a manner analogous to Compound 64C to give the title product. MS m/z 418 (M+1). Step 3. Preparation of {4-[3-(Benzyl-ethyl-amino)-propylsulfanyl]-5-methoxy-2-methyl-phenoxy}-acetic acid (Compound 67)

Sources & evidence

ORD record
ord-0d0310afcc5948aca41025f25e4d1f9d
Source dataset
uspto-grants-2005_04
Patent number
US06875780B2

Reaction notes

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