HuagongsheHuagongshe Chemistry Print Report · For research reference only
2(3H)-Benzoxazolone → (2-oxo-1,3-benzoxazol-3(2H)-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2(3H)-Benzoxazolone | HCID 6043 | — |
| Reactant | Methyl 2-(2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetate | HCID 21349898 | — |
| Product | (2-oxo-1,3-benzoxazol-3(2H)-yl)acetic acid | HCID 737119 | 89% |
Reaction Steps
Compound 76A was prepared analogously to compound 49A using 3H-benzooxazol-2-one. Yield was 89%. 400 MHz 1H NMR (CDCl3) δ 7.1-7.22 (m, 3H), 6.85 (d, 1H), 4.54 (s, 2H), 3.76 (s, 3H). Step 2. Preparation of (6-Chlorosulfonyl-2-oxo-benzooxazo-3-yl}-acetic acid methyl ester (Compound 76B)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875780B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-9e9f082a2b404f1b9906e0e8089181d4 |
| Source note | uspto-grants-2005_04 |