HCID 20770800, compound → HCID 20770804, compound

HRID 1814176Notes

Reaction equation

HRID 1814176 reaction equation
COC(=O)C(C1C=CC(S)=C(OC)C=1)(C)C.[CH3:17][O:18][C:19](=[O:51])[CH2:20][N:21]1[C:25]2[CH:26]=[CH:27][C:28]([S:30]CC3C=CC=C(OCC4C=CC(C(F)(F)F)=CC=4)C=3)=[CH:29][C:24]=2[O:23][C:22]1=[O:50]>>[CH3:17][O:18][C:19](=[O:51])[CH2:20][N:21]1[C:25]2[CH:26]=[CH:27][C:28]([SH:30])=[CH:29][C:24]=2[O:23][C:22]1=[O:50]

Participants

3

Reactant 2

HCID 20770800HCID 20770800, compound2×HCID 207708082-(4-Mercapto-3-methoxy-phenyl)-2-methyl propionic acid methyl ester

Product 1

HCID 20770804HCID 20770804, compoundYield 65%

Procedure

Compound 76C was prepared analogously to compound 21C using the product prepared from compound 76B. Yield was 65%. MS m/z 238 (M−1). Step 4. Preparation of {2-Oxo-6-[3-(4-trifluoromethyl-benzyloxy)-benzylsulfanyl]-benzooxazol-3-yl}-acetic acid methyl ester (Compound 76D)

Sources & evidence

ORD record
ord-44cc6ddcc3ae492f86d0aa2da899fcea
Source dataset
uspto-grants-2005_04
Patent number
US06875780B2

Reaction notes

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