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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814244Generated: November 2, 2026

Ethanolamine → 2-[[(2,3-Difluorophenyl)methyl]thio]-4-[(2-hydroxyethyl)amino]-7(8H)-pteridinone

https://huagongshe.com/reaction/1814244

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant4-bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinoneHCID 22320082—
Product2-[[(2,3-Difluorophenyl)methyl]thio]-4-[(2-hydroxyethyl)amino]-7(8H)-pteridinoneHCID 22506015—

Reaction Steps

The titled compound (52 mg) was prepared from the product of Example 3 step (b) (150 mg) and ethanolamine (35 ul) using the method of Example 2 step (f).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875868B2
Source datasetuspto-grants-2005_04
ORD IDord-31ab3f2358b44d6098ae1e9def4bfe4e
Source noteuspto-grants-2005_04