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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814259Generated: November 1, 2026

5-Methyl-2-furanmethanethiol → 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(5-methyl-2-furanyl)methyl]thio]-7(8H)-pteridinone

https://huagongshe.com/reaction/1814259

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyl-2-furanmethanethiolHCID 521873—
Reactant2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinoneHCID 68817193—
Product4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(5-methyl-2-furanyl)methyl]thio]-7(8H)-pteridinoneHCID 6881414434.3%

Reaction Steps

The titled compound (0.058 g) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 5-methyl-2-furanylmethylmercaptan (0.15 g of 80% pure).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875868B2
Source datasetuspto-grants-2005_04
ORD IDord-98ffefe8167c447b84b6b26c7ffa4f09
Source noteuspto-grants-2005_04