HCID 22505944, compound → HCID 68813203, compound

HRID 1814264Notes

Reaction equation

HRID 1814264 reaction equation
Br[C:2]1[C:11]2[N:10]=[C:9]([CH3:12])[C:8](=[O:13])[NH:7][C:6]=2[N:5]=[C:4]([S:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:17]=2[F:23])[N:3]=1>N[C@@H](CO)C>[F:23][C:17]1[C:18]([F:22])=[CH:19][CH:20]=[CH:21][C:16]=1[CH2:15][S:14][C:4]1[N:3]=[C:2]([NH:10][C@H:9]([CH3:12])[CH2:8][OH:13])[C:11]2[N:10]=[C:9]([CH3:12])[C:8](=[O:13])[NH:7][C:6]=2[N:5]=1

Participants

3

Reactant 1

HCID 22505944HCID 22505944, compound

Product 1

HCID 68813203HCID 68813203, compound

Reagents, catalysts & solvents 1

HCID 80308(R)-(-)-2-Amino-1-propanolSolvent

Procedure

The titled compound was prepared from the product of example 35, step (b) (200 mg) and D-alaninol (120 μl) using the method of Example 2, step (f).

Sources & evidence

ORD record
ord-eb94968a81f64519887dcb149f7a445f
Source dataset
uspto-grants-2005_04
Patent number
US06875868B2

Reaction notes

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