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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814266Generated: November 2, 2026

Bromoform → 4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl Ester

https://huagongshe.com/reaction/1814266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoformHCID 5558—
Reactant4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl EsterHCID 68816120—
Product4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl EsterHCID 86600021—

Reaction Steps

The sub-titled compound was prepared from the product of example 36, step (a) (2 g) and bromoform (40 ml) using the method of Example 3, step (b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875868B2
Source datasetuspto-grants-2005_04
ORD IDord-5bcabe344bff41fb992881026bd9a1b9
Source noteuspto-grants-2005_04