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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814267Generated: November 2, 2026

2-[[(2,3-Difluorophenyl)methyl]thio]-4,5,6-pyrimidinetriamine → 4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-6-(trifluoromethyl)-7(8H)-pteridinone

https://huagongshe.com/reaction/1814267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[[(2,3-Difluorophenyl)methyl]thio]-4,5,6-pyrimidinetriamineHCID 22288503—
ReactantTrifluoropyruvateHCID 22506014—
Product4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-6-(trifluoromethyl)-7(8H)-pteridinoneHCID 22506019—

Reaction Steps

The sub-titled compound was prepared from the product of Example 2, step (c) (5 g) and trifluoropyruvate (10 ml) using the method of Example 2, step (d).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875868B2
Source datasetuspto-grants-2005_04
ORD IDord-9ce7b88cb09d4432aa0a72f18a870899
Source noteuspto-grants-2005_04