HCID 87954650, compound → HCID 86588196, compound

Participants

Reaction Steps

A solution of N-methoxy-N-methyl-3-[2-(2-naphthalen-1-yl-ethoxy)-4-nitro-benzenesulfonylamino]-succinamic acid tert-butyl ester (0.52 g) in tetrahydrofuran (35 mL) and ethanol (35 mL) was treated with RaNi (0.3 g) and hydrogenated at 50 psi. The solution was filtered through Celite and evaporated to give the desired aniline derivative 3-[4-amino-2-(2-naphthalen-1-yl-ethoxy)-benzenesulfonylamino]-N-methoxy-N-methyl-succinamic acid tert-butyl ester (0.45 g) as an amorphous foam.

Provenance & Evidence