Boron Trichloride → 2,4-Dihydroxybenzonitrile

HRID 1814398Notes

Reaction equation

HRID 1814398 reaction equation
C[O:2][C:3]1[CH:10]=[C:9]([O:11]C)[CH:8]=[CH:7][C:4]=1[C:5]#[N:6].B(Cl)(Cl)Cl>>[OH:2][C:3]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:4]=1[C:5]#[N:6]

Participants

3

Reactant 2

HCID 25135Boron TrichlorideHCID 777502,4-Dimethoxybenzonitrile

Product 1

HCID 30175202,4-Dihydroxybenzonitrile

Procedure

2,4-Dimethoxybenzoic acid is reacted with hydroxylamine to form 2,4-dimethoxybenzaldoxime. 2,4-Dimethoxybenzaldoxime is reacted with diphosphorus pentoxide to form 2,4-dimethoxybenzonitrile. 2,4-Dimethoxybenzonitrile is reacted with boron trichloride to form 2,4-dihydroxybenzonitrile.

Sources & evidence

ORD record
ord-cfb6e11cc0f94c86bb48d73605a3cc1c
Source dataset
uspto-grants-2005_04
Patent number
US06875883B2

Reaction notes

Loading…