HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814488Generated: October 31, 2026
Methylamine → N,2-Dimethyl-3-pyridinecarboxamide
https://huagongshe.com/reaction/1814488
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 2-methylnicotinate | HCID 74401 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N,2-Dimethyl-3-pyridinecarboxamide | HCID 12833322 | 95% |
Reaction Steps
To ethyl 2-methylnicotinate (24.2 g) was added a solution of 40% methylamine in methanol (150 ml), which was then heated in a sealed tube at 50° C. overnight. The reaction mixture was evaporated, to give the title compound as a pale yellow solid (20.781 g, yield; 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06875761B2 |
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| Source dataset | uspto-grants-2005_04 |
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| ORD ID | ord-0f373dbeb43b4898aed0ba74624f8db3 |
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| Source note | uspto-grants-2005_04 |
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