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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814517Generated: October 25, 2026

N-methyl-2-toluamide → 3-(4-(n-Butyl)phenyl]isoquinolin-1-one

https://huagongshe.com/reaction/1814517

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-toluamideHCID 75111—
Reactant4-ButylbenzonitrileHCID 140730—
Product3-(4-(n-Butyl)phenyl]isoquinolin-1-oneHCID 2250288931.5%

Reaction Steps

According to the method of Example 10-1, N-methyl-2-methylbenzamide (4.28 g) and 4-(n-butyl)benzonitrile (4.57 g) were reacted, to give 3-[4-(n-butyl)phenyl]isoquinolin-1-one (2.51 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875761B2
Source datasetuspto-grants-2005_04
ORD IDord-2613b2615a00401faf5d017d12027ed9
Source noteuspto-grants-2005_04