Aniline → 5-Methylsulfonyl-2-methylphenyl isocyanate

HRID 1814650Notes

Reaction equation

[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([CH3:14])=[C:9]([N+:11]([O-])=O)[CH:10]=1)(=[O:4])=[O:3].NC1C=CC=CC=1.[N-]=[C:23]=[O:24]>>[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([CH3:14])=[C:9]([N:11]=[C:23]=[O:24])[CH:10]=1)(=[O:4])=[O:3]

Participants

Reactant 3

HCID 6115Aniline

HCID 105034Isocyanate

HCID 6871254-Mesyl-2-nitrotoluene

Product 1

HCID 225019075-Methylsulfonyl-2-methylphenyl isocyanate

Procedure

5-Methylsulfonyl-2-methylphenyl isocyanate was prepared from the corresponding 5-methylsulfonyl-2-methyl-1-nitrobenzene via reduction to the corresponding aniline followed by conversion to the isocyanate as described previously.

Sources & evidence

ORD record: ord-094479bd37514063838972d25eca0d42
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06875760B2

Reaction notes

Loading…