HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → methyl N,N-bis(2-chloroethyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Bis(2-chloroethyl)amine hydrochloride | HCID 522769 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | methyl N,N-bis(2-chloroethyl)carbamate | HCID 327143 | — |
Reaction Steps
The starting material N,N-bis-(2-chloroethyl)-carbamic acid methyl ester is prepared by treating a solution of bis-(2-chloroethyl)-amine hydrochloride in methylene chloride at 0° C. with methyl chloroformate (1.0 mole equivalent) and diisopropylethylamine (2.2 mole equivalents).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06878707B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-54fc4762c10a4701b200bd7633ba31a6 |
| Source note | uspto-grants-2005_04 |