HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 5-(Allyloxy)-2-ethoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Ethoxy-5-hydroxybenzonitrile | HCID 21973177 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-(Allyloxy)-2-ethoxybenzonitrile | HCID 21973188 | — |
Reaction Steps
25 g of 2-ethoxy-5-hydroxybenzonitrile (153.2 mmol) (example 36A) and potassium carbonate (63.52 g, 459.6 mmol) are initially charged in 750 ml of acetone. 19.9 ml of allyl bromide (229.8 mmol) are added, and the mixture is stirred under reflux overnight. The mixture is filtered off and concentrated giving a mobile orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06878708B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-4ebb451c2deb46b0b5deb7c3a7096d21 |
| Source note | uspto-grants-2005_04 |