HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814856Generated: October 25, 2026
1-Carbethoxy-4-ethylamino-3-methylpiperidine → 4-Ethylamino-3-methylpiperidine
https://huagongshe.com/reaction/1814856
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Carbethoxy-4-ethylamino-3-methylpiperidine | HCID 22278900 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-Ethylamino-3-methylpiperidine | HCID 22278859 | — |
Reaction Steps
1-Carbethoxy-4-ethylamino-3-methylpiperidine (2.3 g, 10.74 mmol) was suspended in 5 M NaOH solution (15 ml), stirred at 110° C. for 120 hr, cooled, extracted with ethyl acetate, dried (Na2SO4) and concentrated to dryness to afford 4-ethylamino-3-methylpiperidine. Yield 0.7 g (46%), C8H18N2, m/z 143, (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06878713B2 |
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| Source dataset | uspto-grants-2005_04 |
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| ORD ID | ord-7c81572937964c84ad9ea0cf4f9f1b4a |
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| Source note | uspto-grants-2005_04 |
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