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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814897Generated: November 3, 2026

HCID 10237594, compound → N-(4-Chlorobenzyl)-2-(4-(2-furyl)-4-hydroxybut-1-ynyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide

https://huagongshe.com/reaction/1814897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10237594HCID 10237594—
Reactant1-(2-Furyl)but-3-yn-1-olHCID 10909623—
ProductN-(4-Chlorobenzyl)-2-(4-(2-furyl)-4-hydroxybut-1-ynyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamideHCID 10217000—

Reaction Steps

Analogous to the procedures described in Example 88, 2-bromo-N-(4-chlorobenzyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide (Example 79) is treated with 1-(2-furyl)but-3-yn-1-ol (Preparation 74) to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06878705B2
Source datasetuspto-grants-2005_04
ORD IDord-6e9046da28364c22803480495c8c928a
Source noteuspto-grants-2005_04