HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10237594, compound → N-(4-Chlorobenzyl)-2-(4-hydroxy-4-pyridin-3-ylbut-1-ynyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10237594 | HCID 10237594 | — |
| Reactant | 1-(Pyridin-3-yl)but-3-yn-1-ol | HCID 13193251 | — |
| Product | N-(4-Chlorobenzyl)-2-(4-hydroxy-4-pyridin-3-ylbut-1-ynyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide | HCID 10217168 | — |
Reaction Steps
Analogous to the procedures described in Example 88, 2-bromo-N-(4-chlorobenzyl)-7-methyl-4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide (Example 79) is treated with 1-(pyridin-3-yl)but-3-yn-1-ol (Preparation 75) to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06878705B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-12f3ed2a457e4e569054eb2cf75cd2fc |
| Source note | uspto-grants-2005_04 |