HCID 9882178, compound → HCID 9860534, compound

HRID 1814948Notes

Reaction equation

HRID 1814948 reaction equation
[CH3:1][N:2]1[C:10]2[N:9]=[N:8][N:7]([CH3:11])[C:6]=2[C:5](=[O:12])[N:4]([CH2:13][CH2:14][CH2:15][CH2:16][C@H:17]([OH:19])[CH3:18])[C:3]1=[O:20].[CH3:21][N:22]1[C:30]2[C:26](=[N:27][N:28]([CH3:31])[N:29]=2)[C:25](=[O:32])[N:24]([CH2:33][CH2:34][CH2:35][CH2:36][C@H:37]([OH:39])[CH3:38])[C:23]1=[O:40].C(O[C@@H](C)CCCCCl)(=O)C>>[CH3:1][N:2]1[C:10]2[N:9]=[N:8][N:7]([CH3:11])[C:6]=2[C:5](=[O:12])[N:4]([CH2:13][CH2:14][CH2:15][CH2:16][C@@H:17]([OH:19])[CH3:18])[C:3]1=[O:20].[CH3:21][N:22]1[C:30]2[C:26](=[N:27][N:28]([CH3:31])[N:29]=2)[C:25](=[O:32])[N:24]([CH2:33][CH2:34][CH2:35][CH2:36][C@@H:37]([OH:39])[CH3:38])[C:23]1=[O:40]

Participants

5

Reactant 3

HCID 9882178HCID 9882178, compoundHCID 10221356HCID 10221356, compoundHCID 59743051HCID 59743051, compound

Product 2

HCID 9860534HCID 9860534, compoundHCID 11701891HCID 11701891, compound

Procedure

(S)-3,7-Dimethyl-1-(5-hydroxyhexyl)-8-azaxanthine (CT22464) and (S)-3,8-dimethyl-1-(5-hydroxyhexyl)-8-azaxanthine (CT22465) were synthesized according to the methods described for (R)-3,7-dimethyl-1-(5-hydroxyhexyl)-8-azaxanthine (CT12464) and for (R)-3,8-dimethyl-1-(5-hydroxyhexyl)-8-azaxanthine (CT12465) but using (S)-5-acetoxy-1-chlorohexane in place of (R)-5-acetoxy-1-chlorohexane.

Sources & evidence

ORD record
ord-e6aaa2a536274b2cbea70864a30d6571
Source dataset
uspto-grants-2005_04
Patent number
US06878715B1

Reaction notes

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