4-[{(N-(2-Amino-4,5-difluorobenzoyl)glycyl)amino}methyl]piperidine → 4-[[N-(2-amino-5-trifluoromethylbenzoyl)glycyl]aminomethyl]piperidine
Reaction equation
[C:24]([O:25][C:26]([NH:27][c:28]1[cH:29][cH:30][c:31]([O:32][C:33]([F:34])([F:35])[F:36])[cH:37][c:38]1[C:39]([NH:40][CH2:41][C:42]([NH:43][CH2:44][CH:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1)=[O:51])=[O:52])=[O:53])([CH3:54])([CH3:55])[CH3:56].[C:57]([O:58][C:59](=[O:60])[NH:64][c:65]1[c:66]([C:67](=[O:68])[NH:69][CH2:70][C:71](=[O:72])[NH:73][CH2:74][CH:75]2[CH2:76][CH2:77][NH:78][CH2:79][CH2:80]2)[cH:81][c:82]([C:85]([F:86])([F:87])[F:88])[cH:83][cH:84]1)([CH3:61])([CH3:62])[CH3:63].[NH2:1][c:2]1[cH:3][c:4]([F:5])[c:6]([F:7])[cH:8][c:9]1[C:10]([NH:11][CH2:12][C:13]([NH:14][CH2:15][CH:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1)=[O:22])=[O:23]>>[NH2:64][c:65]1[c:66]([C:67](=[O:68])[NH:69][CH2:70][C:71](=[O:72])[NH:73][CH2:74][CH:75]2[CH2:76][CH2:77][NH:78][CH2:79][CH2:80]2)[cH:81][c:82]([C:85]([F:86])([F:87])[F:88])[cH:83][cH:84]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b0d5c2a5a751475287ca1e52119abf23
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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