huagongshe.com
HRID1815064

反应详情

EQUATION

反应方程式

HRID 1815064 的结构方程式

REACTANTS

反应物

3
结构：Fc1ccncc1
HCID136504

4-Fluoropyridine

C5H4FN

结构：CC(C)(C)OC(=O)N1CCC(O)CC1
HCID643502

n-boc-4-hydroxypiperidine

C10H19NO3

结构：CC(C)(C)OC(=O)N1CCC(Oc2ccccn2)CC1
HCID21906039

tert-Butyl 4-[(pyridin-2-yl)oxy]piperidine-1-carboxylate

C15H22N2O3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(Oc2ccncc2)CC1
HCID21906087

tert-Butyl 4-[(pyridin-4-yl)oxy]piperidine-1-carboxylate

C15H22N2O3

PROCEDURE

实验过程

Prepared from 1-Boc-4-hydroxypiperidine and 4-fluoropyridine using methods substantially equivalent to those described for the synthesis of 1-Boc-4-(pyridin-2-yloxy)piperidine. The product was purified by chromatography over silica gel, eluting with ethyl acetate.

WORKUP

后处理

  1. customThe product was purified by chromatography over silica gel
  2. washeluting with ethyl acetate