HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-formyl-4-methyl-1H-pyrrole-2-carboxylate → 4-Methyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-formyl-4-methyl-1H-pyrrole-2-carboxylate | HCID 9834057 | — |
| Reactant | Indol-2-one | HCID 17904787 | — |
| Product | 4-Methyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic acid methyl ester | HCID 54165653 | 81% |
Reaction Steps
Oxoindole (105 mg, 0.79 mmol) was condensed with 5-formyl-4-methyl-1H-pyrrole-2-carboxylic acid methyl ester (110 mg, 0.67 mmol) using method E to give 153.2 mg (81%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06878733B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-7935f83ca24748c0b9ace0c6a989c9ce |
| Source note | uspto-grants-2005_04 |