6-Phenyl-1,3-dihydro-indol-2-one → HCID 67281795, compound

HRID 1815286Notes

Reaction equation

HRID 1815286 reaction equation
[C:1]1([C:7]2[CH:15]=[C:14]3[C:10]([CH2:11][C:12](=[O:16])[NH:13]3)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:17]([N:19]([CH2:33][CH3:34])[CH2:20][CH2:21][N:22]([CH3:32])[C:23]([C:25]1[NH:26][C:27]([CH:30]=O)=[CH:28][CH:29]=1)=[O:24])[CH3:18]>>[CH2:33]([N:19]([CH2:17][CH3:18])[CH2:20][CH2:21][N:22]([CH3:32])[C:23]([C:25]1[NH:26][C:27]([CH:30]=[C:11]2[C:10]3[C:14](=[CH:15][C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[CH:8][CH:9]=3)[NH:13][C:12]2=[O:16])=[CH:28][CH:29]=1)=[O:24])[CH3:34]

Participants

3

Reactant 2

HCID 105363846-Phenyl-1,3-dihydro-indol-2-oneHCID 86586195HCID 86586195, compound

Product 1

HCID 67281795HCID 67281795, compoundYield 63%

Procedure

6-Phenyl-1,3-dihydroindol-2-one (209 mg, 1 mmol) was condensed with 5-formyl-1H-pyrrole-2-carboxylic acid (2-diethylaminoethyl)methylamide to give 277 mg (63%) of the title compound.

Sources & evidence

ORD record
ord-a3358fa8b55c419aa6fe8512a1a53ad4
Source dataset
uspto-grants-2005_04
Patent number
US06878733B1

Reaction notes

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