6-(2-Methoxyphenyl)-1,3-dihydroindol-2-one → HCID 67281646, compound

HRID 1815306Notes

Reaction equation

HRID 1815306 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:17]=[C:16]2[C:12]([CH2:13][C:14](=[O:18])[NH:15]2)=[CH:11][CH:10]=1.[N:19]1([CH2:24][CH2:25][NH:26][C:27]([C:29]2[C:33]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)=[C:32]([CH:40]=O)[NH:31][C:30]=2[CH3:42])=[O:28])[CH2:23][CH2:22][CH2:21][CH2:20]1>>[N:19]1([CH2:24][CH2:25][NH:26][C:27]([C:29]2[C:33]([C:34]3[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=3)=[C:32]([CH:40]=[C:13]3[C:12]4[C:16](=[CH:17][C:9]([C:4]5[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=5[O:2][CH3:1])=[CH:10][CH:11]=4)[NH:15][C:14]3=[O:18])[NH:31][C:30]=2[CH3:42])=[O:28])[CH2:20][CH2:21][CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 105619756-(2-Methoxyphenyl)-1,3-dihydroindol-2-oneHCID 86586205HCID 86586205, compound

Product 1

HCID 67281646HCID 67281646, compoundYield 35%

Procedure

6-(2-Methoxyphenyl)-1,3-dihydroindol-2-one (50 mg, 0.21 mmol) was condensed with 5-formyl-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide (70 mg) to give 0.04 g (35%) of the title compound as a yellow-orange solid.

Sources & evidence

ORD record
ord-4b55081e723146e7a6d1b4a61c414424
Source dataset
uspto-grants-2005_04
Patent number
US06878733B1

Reaction notes

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