HCID 70147433, compound → HCID 86601534, compound

Participants

Reaction Steps

The title compound was prepared by the procedures described in Example 226, substituting the ethyl ester from Example 225 with the ethyl ester from Example 242, giving a light-yellow solid. 1H NMR (CDCl3, 300 MHz) δ 1.18 (d, J=6.9 Hz, 6H), 1.40-1.89 (m, 5H), 2.34 (br d, J=11.7 Hz, 1H), 3.31-3.51 (m, 1H), 3.44 (septet, J=6.9 Hz, 1H), 4.01 (d, J=11.7 Hz, 1H), 5.42 (br s, 1H), 6.70 (d, J=7.8 Hz, 1H), 6.99 (br d, J=15.6 Hz, 1H), 7.29 (td, J=2.7, 6.9 Hz, 1H), 7.41 (d, J=7.8 Hz, 1H), 7.45-7.58 (m, 3H), 7.64 (d, J=15.6 Hz, 1H), 8.43 (s, 1H). MS (ESI+) (M+H)+ at m/z 455. Anal. Calcd for C24H26N2O5S.0.08 H2O: C, 63.22; H, 5.78; N, 6.14. Found: C, 63.21; H, 5.65; N, 6.00.

Provenance & Evidence