2-Methylfuran → 1-Methyl-2,3-bis(trifluoromethyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene

Participants

Reaction Conditions

Reaction Steps

Hexafluoro-2-butyne (21.0 g, 0.13 mol) was transferred into a reaction bottle and treated with 2-methylfuran (12.86 g, 0.157 mol). This resulting mixture bottle was sealed and heated for 15 hours at 120° C. After cooling, the excess 2-methylfuran was rotoevaporated in vacuo at room temperature, to give the crude title product (29 g, 92%), which was used directly.

Provenance & Evidence