HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Benzyl-N-tert-butylcyclopropane-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | N-tert-butyl-1-methylcyclopropane-1-sulfonamide | HCID 21889792 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 1-Benzyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889796 | 60% |
Reaction Steps
Steps 7Ib-7Ic) This compound was obtained in 60% yield using the procedure described for the synthesis of N-tert-Butyl-(1-methyl)cyclopropylsulfonamide except 1.05 equivalents of benzyl bromide were used, followed by trituration with 10% EtOAc in hexane: 1H NMR (CDCl3) δ 0.92 (m, 2H), 1.36 (m, 2H), 1.43 (s, 9H), 3.25 (s, 2H), 4.62 (bs, 1H), 7.29-7.36 (m, 5H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06878722B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-dba2fcc1d9b8406db8c3a862d3bf02b3 |
| Source note | uspto-grants-2005_04 |