HCID 9818386, compound → HCID 9948421, compound

HRID 1815789Notes

Reaction equation

HRID 1815789 reaction equation
[OH:1][CH2:2][C@@H:3]1[CH2:8][CH2:7][C@:6]2(C)[C@H:9]3[C@H:18]([CH2:19][CH2:20][C@:4]12[CH3:5])[C@@H:17]1[C:12](=[CH:13][C:14](=[O:21])[CH2:15][CH2:16]1)[CH2:11][C@H:10]3[CH3:22].OC[C@@H]1CC[C@@H]2[C@H]3[C@H](CC[C@]12C)[C@@H]1C(=CC(=O)CC1)C[C@H]3C>O1CCOCC1>[OH:1][CH2:2][C@@H:3]1[CH2:8][CH2:7][C@@H:6]2[C@H:9]3[C@H:18]([CH2:19][CH2:20][C@:4]12[CH3:5])[C@@H:17]1[C:12](=[CH:13][C@@H:14]([OH:21])[CH2:15][CH2:16]1)[CH2:11][C@H:10]3[CH3:22]

Participants

4

Reactant 2

HCID 9818386HCID 9818386, compoundHCID 9861223HCID 9861223, compound

Product 1

HCID 9948421HCID 9948421, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Following a procedure analogous to that described under ix of Example 6, the title compound was prepared from (7α,14β,17α)-17-(hydroxymethyl)-7-methylestr-4-en-3-one (Example 4). [α]D20=+28.2° (c=0.49, dioxane).

Sources & evidence

ORD record
ord-604a934cea474133a695e04024f8dc34
Source dataset
uspto-grants-2005_04
Patent number
US06881728B1

Reaction notes

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