HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 6H-oxazolo[4,5-e]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 5-Hydroxyindole | HCID 16054 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6H-oxazolo[4,5-e]indole | HCID 11332609 | — |
Reaction Steps
0.5 mmol of methylamine and 4.13 mmol of MnO2 are added to a solution of 0.4 mmol of 5-hydroxy-1H-indole in 3 ml of DMF, and the mixture is stirred at room temperature for 18 hours. The suspension is filtered through Celite and subjected to conventional work-up, giving 6H-oxazolo[4,5-e]indole; ESI 159.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741343B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-48e2ebd3ce31455ea6dd59c9383f0a06 |
| Source note | uspto-grants-2010_06 |