HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-3-methyl-4-piperidone → 1-Benzyl-3-methyl-4-hydroxy-4-(5-chlorobenzofur-7-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-3-methyl-4-piperidone | HCID 560965 | — |
| Reactant | 7-Bromo-5-chloro-1-benzofuran | HCID 22144720 | — |
| Product | 1-Benzyl-3-methyl-4-hydroxy-4-(5-chlorobenzofur-7-yl)piperidine | HCID 22495631 | 92% |
Reaction Steps
Beginning with 4.0 gm (17.3 mMol) 5-chloro-7-bromobenzofuran and 3.86 gm (19.0 mMol) 1-benzyl-3-methyl-4-oxo-piperidine, 5.6 gm (92%) of the desired compound were recovered essentially as described in EXAMPLE 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06881733B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-25c0608edb564a4289cc27a17156d41d |
| Source note | uspto-grants-2005_04 |