HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-3-methyl-4-piperidone → 1-Benzyl-3-methyl-4-hydroxy-4-(2-methylbenzofur-7-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-3-methyl-4-piperidone | HCID 560965 | — |
| Reactant | 7-Bromo-2-methyl-1-benzofuran | HCID 12264721 | — |
| Product | 1-Benzyl-3-methyl-4-hydroxy-4-(2-methylbenzofur-7-yl)piperidine | HCID 22495627 | 66.7% |
Reaction Steps
Beginning with 1.0 gm (4.74 mMol) 2-methyl-7-bromobenzofuran and 1.01 gm (4.98 mMol) 1-benzyl-3-methyl-4-oxopiperidine, 1.06 gm of the desired compound was prepared as an orange oil essentially as described in EXAMPLE 19.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06881733B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-797153a5596d4279a8d0ef0eab866615 |
| Source note | uspto-grants-2005_04 |