HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylstannane → HCID 69744971, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | HCID 22495600 | HCID 22495600 | — |
| Reactant | HCID 22495776 | HCID 22495776 | — |
| Product | HCID 69744971 | HCID 69744971 | 90.4% |
Reaction Steps
Beginning with 0.50 gm (1.47 mMol) 1-benzyl-3-methyl-4-hydroxy-4-(5-fluorobenzofur-4-yl)piperidine, 1-benzyl-3-methyl-4-(methyl oxoacetoxy)-4-(5-fluorobenzofur-4-yl)piperidine was prepared essentially as described in EXAMPLE 16. This material was treated with tri(n-butyl)tin hydride essentially as described in EXAMPLE 16 to prepare 0.43 gm (80%) of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06881733B1 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-cfc460235b9d44349c65d1a4055b608c |
| Source note | uspto-grants-2005_04 |