1-Chloroethyl chloroformate → HCID 22495658, compound

HRID 1815882Notes

Reaction equation

HRID 1815882 reaction equation
C([N:8]1[CH2:12][CH2:11][CH:10]([C:13]2[C:21]3[O:20][CH:19]=[CH:18][C:17]=3[CH:16]=[C:15]([F:22])[CH:14]=2)[CH2:9]1)C1C=CC=CC=1.[Cl:23]C(OC(Cl)C)=O>>[ClH:23].[F:22][C:15]1[CH:14]=[C:13]([CH:10]2[CH2:11][CH2:12][NH:8][CH2:9]2)[C:21]2[O:20][CH:19]=[CH:18][C:17]=2[CH:16]=1

Participants

3

Reactant 2

HCID 5213051-Chloroethyl chloroformateHCID 22495561HCID 22495561, compound

Product 1

HCID 22495658HCID 22495658, compound

Procedure

1-Benzyl-3-(5-fluorobenzofur-7-yl)pyrrolidine was debenzylated with 1-chloroethyl chloroformate and converted to the free amine, essentially as described in EXAMPLE 3.

Sources & evidence

ORD record
ord-9d4472ab9e534b4299ee5c00d9992d02
Source dataset
uspto-grants-2005_04
Patent number
US06881733B1

Reaction notes

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