HCID 20775651, compound → HCID 86759661, compound

Participants

Reaction Steps

A mixture of methyl (±)-3-[4-(benzyloxycarbonyl)-1,3-oxazol-2-yl]-4-[4-[(tert-butyloxycarbonyl)oxy]phenyl]butanoate (765 mg, 1.54 mmole) and 10% Pd/C (164 mg) in EtOH (20 mL) was deoxygenated (3×evacuation/N2 purge cycles) then was charged with H2 (50 psi). After 4 hr the H2 was removed and the mixture was filtered through a pad of celite®. The filtrate was concentrated to afford the title compound (659 mg, 100%) as a white solid: MS (ES) m/e 811 (2M+H)+.

Provenance & Evidence