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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816073Generated: November 1, 2026

chloro-5-[3-[(methylsulfonyl)oxy]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide → 2-Chloro-5-[3-[[2-(1H-imidazol-4-yl)ethyl]amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)benzamide

https://huagongshe.com/reaction/1816073

Reaction equation

Participants

RoleNameHCIDCharge
Reactantchloro-5-[3-[(methylsulfonyl)oxy]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamideHCID 12988688—
ReactantHCID 178419017HCID 178419017—
Product2-Chloro-5-[3-[[2-(1H-imidazol-4-yl)ethyl]amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)benzamideHCID 178522744—

Reaction Steps

Synthesized from 2-chloro-5-[3-[(methylsulfonyl)oxy]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide (Example 6e, 1 mg) and histamine according to the procedure described in Example 6f to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06881754B2
Source datasetuspto-grants-2005_04
ORD IDord-53f9a9950f0442f9aceeee706777a12e
Source noteuspto-grants-2005_04