Sodium Hydroxide → 439291-60-8

HRID 1816239Notes

Reaction equation

HRID 1816239 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8](C)=[N:7][C:6]=2[CH:11]=1.[OH-].[Na+]>C(O)CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:8])=[C:6]([CH:11]=1)[NH2:7]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 5974375-Fluoro-2-methylbenzothiazole

Product 1

HCID 11019126439291-60-8

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

5-Fluoro-2-methylbenzothiazole was heated with ethylene glycol and 10N sodium hydroxide solution and the resulting thiol methylated using procedures similar to those described in Example 5, to give 5-fluoro-2-(methylthio)aniline.

Sources & evidence

ORD record
ord-4c7d03718dc94128be4bacc7dd1c135c
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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