Fumaric Acid → HCID 131724843, compound

HRID 1816241Notes

Reaction equation

HRID 1816241 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[NH:9]1[CH2:13][CH2:12][N:11]=[C:10]1[CH2:14][NH:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[S:22]([CH3:24])=[O:23]>CO>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[NH:11]1[CH2:12][CH2:13][N:9]=[C:10]1[CH2:14][NH:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[S:22]([CH3:24])=[O:23]

Participants

4

Reactant 2

HCID 444972Fumaric AcidHCID 11747739HCID 11747739, compound

Product 1

HCID 131724843HCID 131724843, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The later eluting enantiomer from Example 12 (24 min) was converted to its fumaric acid salt and determined to be (+)-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(methylsulfinyl)aniline by measurement of its optical rotation in methanol.

Workup

  1. customfrom Example 12 (24 min)

Sources & evidence

ORD record
ord-766b291f0a1b4befb1b4ba9fd07ff597
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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