Isatoic Anhydride → HCID 10221183, compound

HRID 1816246Notes

Reaction equation

HRID 1816246 reaction equation
[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH3:10])[CH2:7][CH2:8][CH3:9])=[O:5].[CH3:15][NH:16][CH2:17][CH2:18]C.C12C(=CC=CC=1)[NH:25][C:24](=O)OC2=O>>[NH:16]1[CH2:15][CH2:24][N:25]=[C:17]1[CH2:18][NH:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH3:10])[CH2:7][CH2:8][CH3:9])=[O:5]

Participants

4

Reactant 3

HCID 8359Isatoic AnhydrideHCID 12315N-MethylpropylamineHCID 22493435HCID 22493435, compound

Product 1

HCID 10221183HCID 10221183, compound

Procedure

2-Amino-N-methyl-N-propylbenzamide (prepared from N-methylpropylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-methyl-N-propylbenzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3e3b1b276da3458a80920699710fbb9c
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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