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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816252Generated: November 1, 2026

1-Amino-2-propanol → HCID 22493328, compound

https://huagongshe.com/reaction/1816252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-2-propanolHCID 4—
ReactantIsatoic AnhydrideHCID 8359—
Reactant2-Amino-N-(2-hydroxypropyl)benzamideHCID 12562298—
ProductHCID 22493328HCID 22493328—

Reaction Steps

2-Amino-N-(2-hydroxypropyl)benzamide (prepared from 1-amino-2-propanol and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino)-N-(2-hydroxypropyl)benzamide, isolated as the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884801B1
Source datasetuspto-grants-2005_04
ORD IDord-4c9a3549e19b46efb71184f873f3e785
Source noteuspto-grants-2005_04