Dimethylamine → HCID 22493320, compound

HRID 1816254Notes

Reaction equation

HRID 1816254 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([N:6]([CH3:8])[CH3:7])=[O:5].[CH3:13][NH:14]C.C12[C:22](=[CH:23]C=CC=1)[NH:21][C:20](=O)OC2=O>>[NH:21]1[CH2:20][CH2:13][N:14]=[C:22]1[CH2:23][NH:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([N:6]([CH3:8])[CH3:7])=[O:5]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 8359Isatoic AnhydrideHCID 47781752-Amino-N,N-dimethylbenzamide

Product 1

HCID 22493320HCID 22493320, compound

Procedure

2-Amino-N,N-dimethylbenzamide (prepared from dimethylamine [2M in tetrahydrofuran]and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N,N-dimethylbenzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-20facfdeb08340b2961b06f43fbc78cc
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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