Pentylamine → HCID 22493404, compound

HRID 1816255Notes

Reaction equation

HRID 1816255 reaction equation
[NH2:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])=[O:5].[CH2:16]([NH2:21])[CH2:17]CCC.[C:22]12[C:28](=CC=CC=1)[NH:27]C(=O)OC2=O>>[NH:27]1[CH2:28][CH2:22][N:21]=[C:16]1[CH2:17][NH:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])=[O:5]

Participants

4

Reactant 3

HCID 8060PentylamineHCID 8359Isatoic AnhydrideHCID 16770058HCID 16770058, compound

Product 1

HCID 22493404HCID 22493404, compound

Procedure

2-Amino-N-pentylbenzamide (prepared from amylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-pentylbenzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-50d56e1d60b04d00bbc23a05126846d3
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

Loading…