Isatoic Anhydride → HCID 22493401, compound

HRID 1816256Notes

Reaction equation

HRID 1816256 reaction equation
[NH2:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([N:6]([CH2:10][CH3:11])[CH2:7][CH2:8][CH3:9])=[O:5].[CH2:16]([NH:18][CH2:19][CH2:20]C)[CH3:17].C12C(=CC=CC=1)[NH:27]C(=O)OC2=O>>[NH:27]1[CH2:20][CH2:19][N:18]=[C:16]1[CH2:17][NH:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([N:6]([CH2:10][CH3:11])[CH2:7][CH2:8][CH3:9])=[O:5]

Participants

4

Reactant 3

HCID 8359Isatoic AnhydrideHCID 883981-Propanamine, N-ethyl-HCID 22493329HCID 22493329, compound

Product 1

HCID 22493401HCID 22493401, compound

Procedure

2-Amino-N-ethyl-N-propylbenzamide (prepared from N-ethylpropylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)amino]-N-ethyl-N-propylbenzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-df0d8edce6594aab929843acc710f4b2
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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