Isatoic Anhydride → HCID 9903313, compound

HRID 1816259Notes

Reaction equation

HRID 1816259 reaction equation
[NH2:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([N:6]([CH2:8][CH3:9])[CH3:7])=[O:5].[CH2:14]([NH:16][CH3:17])[CH3:15].C12C(=CC=CC=1)[NH:23][C:22](=O)OC2=O>>[NH:16]1[CH2:17][CH2:22][N:23]=[C:14]1[CH2:15][NH:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([N:6]([CH2:8][CH3:9])[CH3:7])=[O:5]

Participants

4

Reactant 3

HCID 8359Isatoic AnhydrideHCID 12219N-MethylethylamineHCID 22493299HCID 22493299, compound

Product 1

HCID 9903313HCID 9903313, compound

Procedure

2-Amino-N-ethyl-N-methylbenzamide (prepared from N-ethylmethylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-ethyl-N-methylbenzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-f9b19d3b58c14d629390d78771db6573
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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