Isatoic Anhydride → HCID 22493411, compound

HRID 1816260Notes

Reaction equation

HRID 1816260 reaction equation
[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][CH:7]([CH2:9][CH3:10])[CH3:8])=[O:5].[CH:15]([NH2:19])([CH2:17]C)C.[C:20]12[C:26](=CC=CC=1)[NH:25]C(=O)OC2=O>>[CH:7]([NH:6][C:4](=[O:5])[C:3]1[CH:11]=[CH:12][CH:13]=[CH:14][C:2]=1[NH:1][CH2:17][C:15]1[NH:19][CH2:20][CH2:26][N:25]=1)([CH2:9][CH3:10])[CH3:8]

Participants

4

Reactant 3

HCID 8359Isatoic AnhydrideHCID 24874Sec-ButylamineHCID 27743072-Amino-N-(butan-2-yl)benzamide

Product 1

HCID 22493411HCID 22493411, compound

Procedure

2-Amino-N-sec-butylbenzamide (prepared from sec-butylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-(sec-butyl)-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzamide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-093ccaf16b5e4df8bd0cc314d173396e
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

Loading…