Isatoic Anhydride → HCID 22493393, compound

HRID 1816269Notes

Reaction equation

HRID 1816269 reaction equation
[C:1]([NH:4][NH:5][C:6](=[O:14])[C:7]1[C:8](=[CH:10][CH:11]=[CH:12][CH:13]=1)[NH2:9])(=[O:3])[CH3:2].[C:15]([NH:18]N)(=O)[CH3:16].[C:20]12[C:26](=CC=CC=1)[NH:25]C(=O)OC2=O>>[C:1]([NH:4][NH:5][C:6](=[O:14])[C:7]1[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=1[NH:9][CH2:16][C:15]1[NH:18][CH2:20][CH2:26][N:25]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 3

HCID 8359Isatoic AnhydrideHCID 14039AcetohydrazideHCID 2611532-Amino-N-(1-hydroxyethylidene)benzene-1-carbohydrazonic acid

Product 1

HCID 22493393HCID 22493393, compound

Procedure

Anthranilic acid N′-acetylhydrazide (prepared from acetic hydrazide and isatoic anhydride using the method described in Example 44) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N′-acetyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzohydrazide.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-5ee031c21f2f479492e2087ea2422e89
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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