Isatoic Anhydride → HCID 22493237, compound

HRID 1816270Notes

Reaction equation

[NH2:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][NH:7][C:8]([CH3:11])([CH3:10])[CH3:9])=[O:5].[C:16]([NH:20]N)([CH3:19])(C)C.[C:22]12[C:28](=CC=CC=1)[NH:27]C(=O)OC2=O>>[C:8]([NH:7][NH:6][C:4](=[O:5])[C:3]1[CH:12]=[CH:13][CH:14]=[CH:15][C:2]=1[NH:1][CH2:19][C:16]1[NH:20][CH2:22][CH2:28][N:27]=1)([CH3:11])([CH3:10])[CH3:9]

Participants

Reactant 3

HCID 8359Isatoic Anhydride

HCID 81890tert-Butylhydrazine

HCID 2797474HCID 2797474, compound

Product 1

HCID 22493237HCID 22493237, compound

Procedure

2-Amino-N′-(tert-butyl)benzohydrazide (prepared from tert-butylhydrazine and isatoic anhydride using the method described in Example 44) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N′-(tert-butyl)-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzohydrazide.

Workup

customwere reacted

Sources & evidence

ORD record: ord-e5c37876d4fd454cacfb95933dc435b7
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06884801B1

Reaction notes

Loading…