反应详情

N-Methyl-2-nitrobenzenesulfonamide (1.0 g, 4.6 mmol), 10% palladium on carbon (100 mg) and absolute ethanol (30 mL) were placed in a Parr bottle, the bottle placed on a Parr apparatus under a hydrogen atmosphere (45 psi), and shaken for 1 hour, The Parr bottle was evacuated and flushed with nitrogen, then the mixture was filtered through a disposable syringe filter. The filtrate was concentrated in vacuo to yield 0.81 g of 2-amino-N-methylbenzenesulfonamide.

1. customThe Parr bottle was evacuated
2. customflushed with nitrogen
3. filtrationthe mixture was filtered through a disposable syringe
4. filtrationfilter
5. concentrationThe filtrate was concentrated in vacuo