Ethylamine → HCID 9903879, compound

HRID 1816273Notes

Reaction equation

HRID 1816273 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][CH2:12][CH3:13])(=[O:10])=[O:9].[N+:14]([C:17]1[CH:22]=CC=CC=1S(Cl)(=O)=O)([O-])=O.[CH2:27]([NH2:29])[CH3:28]>>[NH:14]1[CH2:17][CH2:22][N:29]=[C:27]1[CH2:28][NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][CH2:12][CH3:13])(=[O:10])=[O:9]

Participants

4

Reactant 3

HCID 6341EthylamineHCID 155402-Nitrobenzenesulfonyl chlorideHCID 16785721HCID 16785721, compound

Product 1

HCID 9903879HCID 9903879, compound

Procedure

2-Amino-N-ethylbenzenesulfonamide (prepared from 2-nitrobenzenesulfonyl chloride and ethylamine using the methods described in Example 50) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-ethylbenzenesulfonamide, isolated as the fumarate salt.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-8ccc4e74e1a94418a02a8f4c6e26927e
Source dataset
uspto-grants-2005_04
Patent number
US06884801B1

Reaction notes

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