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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1816392Generated: November 2, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-Methyl-6-[3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)cyclohexyloxymethyl]benzoic Acid

https://huagongshe.com/reaction/1816392

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant2-(4-Methylphenyl)-4-iodomethyl-5-methyloxazoleHCID 21980311—
Product2-Methyl-6-[3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)cyclohexyloxymethyl]benzoic AcidHCID 22493638—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(4-methylphenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 70 of molecular weight 449.55 (C27H31NO5), MS(ESI): 450.36 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06884812B2
Source datasetuspto-grants-2005_04
ORD IDord-42d756fc6e2e43738b00c3050895b2b7
Source noteuspto-grants-2005_04