2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 69754075, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the product from Step A (0.08 g, 0.17 mmol) in 1,4-dioxane (10 mL) was added DDQ (0.08 g, 0.34 mmol). The solution was stirred at 23° C. for 3 hr and poured into saturated aqueous NaHCO3 and this mixture was extracted with ether (2×20 mL). The combined extracts were washed with aqueous NaHCO3, dried (MgSO4), and evaporated to a crude product which was purified by chromatography (silica, 40% ethyl acetate in hexanes) to obtain an oil (0.045 g, 55%): MS m/z: 478 [M+H]+.

Provenance & Evidence